Please help... Fenbendazole-resistant Camallanus and I live in Canada

Shelilla

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Oct 8, 2020
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Have you tested your water?
Yes
If yes, what is your ammonia?
0
If yes, what is your nitrite?
0
If yes, what is your nitrate?
0.5
If I did not test my water...
...I recognize that I will likely be asked to do a test, and that water tests are critical for solving freshwater health problems.
Do you do water changes?
Yes
What percentage of water do you change?
21-30%
How frequently do you change your water?
Every week
If I do not change my water...
...I recognize that I will likely be recommended to do a water change, and water changes are critical for preventing future freshwater health problems.
I’ve come to this forum in hopes of getting some help or advice.. I’ve seen several posts on these awful parasites before and the advice given has been helpful, as people here seem to be knowledgeable and experienced with how parasites work.

It’s my worst nightmare.... I noticed red worms in my very sweet female Gardner’s Killifish about a month after I got her, and immediately called the vet. Got a prescription of Fenbendazole for the next 3 weeks. I’m almost certain it cured everyone else in the tank except this fish... I had one fish with a very swollen stomach which went down quickly after the first dose of meds and has been ever since. And no other fish in the tank have shown any concerning signs.

But the adult worms in this fish have not disappeared after 2 doses and so last week I put this poor fish in a separate container floating in the tank so the worms don’t keep laying eggs for other fish to suffer.

I have a 20g tall tank and have been adding 1.5mL of fenbendazole to the tank after doing a 25% water change every week. I just added the third and final dose yesterday.


I contacted my vet, and asked about Levamisole which is the other meds I’ve seen recommended on many other threads. What he said was that in Canada, it’s not approved for veterinary use and that fenbendazole was the only option he had for treating it. There is one other exotic vet in my city that may have more medication options (my current vet doesn’t advertise to specialize in exotic pets, they just are able to and willing to treat fish in certain cases such as parasites).

I asked on reddit and someone said that fenbendazole kills the younger worms at a normal prescribed dose, but for adult worms you should give a much higher dose to kill them off. So on Monday I added a bit more of it to the small container the fish is in- enough to make the water go pretty white and for precipitate to appear on the bottom the next day. The worms were hanging out her vent quite far, but definitely not dead.
Yesterday, after that third final dose I changed the water and cleaned out the container I was keeping that fish in, then added a strong enough dose of fenbendazole that you can’t see her if she’s at the opposite side of the container. I checked today and there were still worms.

I asked my vet about piperzine, as I saw someone mention this as a treatment option in another forum post and it’s at least legal here. My vet said they could order some in if needed however it’s weaker than fenbendazole. But regardless, is it possible that could do it? I rarely see piperzine recommended as a med to treat camallanus, so is there a chance the worms would have no immunity towards it? If not, should I try getting flubendazole or nematol from the other vet? (I’ve seen these as treatment options on forum posts here too, but I have no idea if these are allowed for veterinary use in canada either)

Please help... this poor fish has been through so much and I feel like there’s so few options available when I want to help her so badly... she’s been so resilient and clearly wants to live because throughout all this stress on her body and mind she has still been active and eating well but is enduring a lot. I want her to live a long happy life as a healthy fish in a good tank, not dying of illness and stress because of parasites she caught from the pet store. It’s not fair to just give up on her because these terrible parasites are resisting meds and my stupid country has closed off treatment options... it’s really not fair.
 

kno4te

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Not sure if it’s resistant. Hard to prove but I’d suggest repeat dosing with febendazole with multiple repeat dosing (3 total). The egg stage is resistant to meds etc. If the dose isn’t repeated then it won’t clear. Seen others use liquid febendazole to the tank and feed febendazole granules with garlic. If none of those work then I’d euthanize the fish. Just IMO. Best of luck!
 

Shelilla

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Oct 8, 2020
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Not sure if it’s resistant. Hard to prove but I’d suggest repeat dosing with febendazole with multiple repeat dosing (3 total). The egg stage is resistant to meds etc. If the dose isn’t repeated then it won’t clear. Seen others use liquid febendazole to the tank and feed febendazole granules with garlic. If none of those work then I’d euthanize the fish. Just IMO. Best of luck!
I forgot to mention in the post, this is a liquid suspended solution and these are the same 2 adult worms that have been hanging out her vent the whole time because they're red with her blood and theres always been 2. Also, I have fed her and all my other fish medicine-soaked food, and she (and other fish) has even eaten the medicine straight when I dropped it in the water as it's quite viscous and doesn't mix fully unless I wave it around, so the fish eat it thinking its food.

And if you read my post fully you would see that I have already dosed for 3 weeks I added the third week dose just yesterday. This has been going on for 2 weeks now.

I am not going to euthanize her so long as there are other options, and you only mentioned fenbendazole. This isn't the only medication to treat these worms, in fact from what I’ve read they’re more often than not immune to fenbendazole anyways so a lot of people just have to keep trying different dewormers. I've considered ordering levamisole off a US seller from aquabid who ships internationally for example, though this is possibly or probably illegal. And I don't even know if nematol is banned here, I don't think it is?
 
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Hybridfish7

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At the stage where the worms are visual, especially in smaller fish, it's a very small chance of survival. For one there's killing the worms, which may or may not work, but when it does there's the problem of secondary bacterial infections, which then may kill the fish. I am going to have to sadly say euthanasia may be the best option to make treating the other fish easier, however if the killi has been in the tank for around 6 weeks it may be too late for the others too. However the visual stage of camallanus is the reproduction stage, which I say is covered by the fenbendazole treatment. When I had a bad outbreak in my fishroom, I treated with levamisole first, then fenbendazole, because levamisole only paralyzes the worms and eggs, but also causes them to be ejected from the fish, making it easier for them to be siphoned out. Fenbendazole kills any eggs or early stage larvae left around the tank or in the fish.
Are you treating the water or feeding the meds to them? It works more effectively when fed, and 2 doses is definitely not enough. I had to go through 2 weeks of treatment to be clear, but even then a quarter of my fishroom died of secondary infections.
 

Shelilla

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Oct 8, 2020
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At the stage where the worms are visual, especially in smaller fish, it's a very small chance of survival. For one there's killing the worms, which may or may not work, but when it does there's the problem of secondary bacterial infections, which then may kill the fish. I am going to have to sadly say euthanasia may be the best option to make treating the other fish easier, however if the killi has been in the tank for around 6 weeks it may be too late for the others too. However the visual stage of camallanus is the reproduction stage, which I say is covered by the fenbendazole treatment. When I had a bad outbreak in my fishroom, I treated with levamisole first, then fenbendazole, because levamisole only paralyzes the worms and eggs, but also causes them to be ejected from the fish, making it easier for them to be siphoned out. Fenbendazole kills any eggs or early stage larvae left around the tank or in the fish.
Are you treating the water or feeding the meds to them? It works more effectively when fed, and 2 doses is definitely not enough. I had to go through 2 weeks of treatment to be clear, but even then a quarter of my fishroom died of secondary infections.
I said in my comment prior i have done both feeding and in the water. The fish is hanging in there but the worms are still present. She has held on for the past 3 weeks with these worms present so she is very tough... however she has been very stressed and pale lately and even more worrying I found several of her eggs laid in the container for some reason. I don’t know if it was an odd side effect of basically overdosing her with fenbendazole or if the worms have caused it but yeah... I am going to give her a couple more days with no more meds and some almond leaves in the container so she can destress and if she does not start eating again after that or improve I will not let her starve to death and will bring her the most peaceful end I can find....

I’m really sad. It’s not fair and she’s been put through so much the past several weeks and kept eating well, being such an active and robust little fish that I feel like the least I can do would be to give her a long healthy life at home instead of a stressful pet store where she caught the parasites.... I just hope she comes back after this
 

Shelilla

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Oct 8, 2020
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I also said in my original post that I just added the third dose yesterday... thats why my vet prescribed 3 for the potential larvae hatching after 3 weeks. I also saved some mixed with tank water to dissolve any stuff that had dried out to also use that if needed
 

Niki_up

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Just for future reference you can get fenbendazole at GE pharmacy for like $3 in Alberta, Canada
 

Shelilla

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Oct 8, 2020
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Thanks for the resources guys... I hope this helps other people being put through this awful experience, and I hope they can have the ability to do more for their fish next time. These parasites are so horrible...

I buried my fish under the sunflowers in the yard.
 
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