Very unlikely Kh/Gh related.
How deep is your well?
Is your area experiencing a big melt right now?
Just wondering about the potential of toxins leaching into the ground water

With deep wells it is likely not usually a problem, but if your well is shallow and in an agricultural area, possibly a ground chemical

Do you have a carbon block filter on your well supply?
We had toxic city water in Toledo back in 2014 causes by microcytins from a blue green algae bloom at the water catchment in Lake Erie. The city x 5 the chlorine/chloramine content to try to make the water safe. I literally had to run my water change water though a carbon block and dose Prime at 5x the dose for 6 whole months or my fish would lay in the bottom black and die.