Depends how strong you 2 are? It should weigh around 350 lbs as my 225 gallon weighed about 400 lbs and it took 4 decent strong guys to move it. 2 on each side. Also ya the more ppl the better, u don't wanna drop the tank and smash it...
You want to give us the most important information? (Is it glass or acrylic?) Me and my dad carried my 300 gallon acrylic tank from the bed of his truck to the backyard. And even for acrylic, it's a thick tank. If it's glass I suggest 3 people, if it's acrylic, then I bet two girls could carry it, lol.