I am still stuck on the nutritional issue. We all know that live feeders out perform frozen or processed diets. There are a lot of reasons, but I haven't been able to quantify the nutritional content of a feeder goldfish yet. I would propose that the main culprit in any fatty buildup in aquarium fish is plain over feeding. It may be more prevalent with feeders than processed diets because of the appetite fish show for live food. If I find a good reference I'll cite it in the future.
Disease is another issue, like over feeding, that we are responsible to manage. Feeders, like all fish, are diseased. A feeder goldfish should never go directly into an aquarium, but rather held in a separate quarantine tank. I would recommend elevated salt levels in the .6 to .8% and prazi at a rate of 1gm per 100 gallons. This regiment eliminates protozoans, flukes and internal parasites. It's a seven day treatment for the prazi, so having two quarantine tanks would be a good idea. But with saltwater tanks, I can't think of a single freshwater disease, common to goldfish, that would survive in a saltwater tank. Freshwater feeders are an excellent diet for saltwater piscivores. Far better than frozen diets or commercial diets made from processed fish meal and grains. The proof is in the superior growth rates and increased appetites. Excessive overfeeding for sure should be avoided.