The anaerobic bacteria live in areas devoid of oxygen, such as deep in the substrate of the aquarium or in areas where decorations cover the substrate. Some of the anaerobic bacteria are beneficial; some of them convert nitrate into nitrogen gas. This is why most denitrators have such slow flow rates and long coiled tubes- the idea is that bacteria will colonize the first part of the tube or denitrator and consume all of the oxygen, so everything from that point on will be anaerobic. In large quantities, anaerobic bacteria are bad because some types produce hydrogen sulfide as a metabolic byproduct. Hydrogen sulfide smells like rotten eggs; in marine aquaria, just stirring an anaerobic pocket can kill the fish. In freshwater it is largely less toxic, but is a symptom of poor husbandry techniques. These anaerobic areas also indicate lost bio filter real estate. Some of the other byproducts of anaerobic respiration are toxic if allowed to build up, but hydrogen sulfide is the most noticeable. The main way to fight anaerobic areas are to avoid placing rocks and decorations in a way that water cannot flow over the surface of the substrate. Decreasing substrate depth or increasing particle size will allow more oxygen to go deeper in the substrate. Fine sand has a tendancy to get packed and turn anaerobic; livestock ranging from Malaysian livebearing snails to horseface loaches to eartheater cichlids to (small) softshell turtles may be needed to prevent anaerobic pockets from forming.